MRST2001: partons and α <SUB>S</SUB> from precise deep inelastic scattering and Tevatron jet data

We use all the available new precise data for deep inelastic and related hard scattering processes to perform NLO global parton analyses. These new data allow an improved determination of partons and, in particular, the inclusion of the recent measurements of the structure functions at HERA and of the inclusive jets at the Tevatron help to determine the gluon distribution and aS better than ever before. We find a somewhat smaller gluon at low x than previous determinations and that aS (MZ2) = 0.119 ±0.002 (expt.) ±0.003 (theory)

Uncertainties of predictions from parton distributions I: experimental errors

We determine the uncertainties on observables arising from the errors on the experimental data that are fitted in the global MRST2001 parton analysis. By diagonalizing the error matrix we produce sets of partons suitable for use within the framework of linear propagation of errors, which is the most convenient method for calculating the uncertainties. Despite the potential limitations of this approach we find that it can be made to work well in practice. This is confirmed by our alternative approach of using the more rigorous Lagrange multiplier method to determine the errors on physical quantities directly. As particular examples we determine the uncertainties on the predictions of the charged-current deep-inelastic structure functions, on the cross-sections for W production and for Higgs boson production via gluon-gluon fusion at the Tevatron and the LHC, on the ratio of W- to W+ production at the LHC and on the moments of the non-singlet quark distributions. We discuss the corresponding uncertainties on the parton distributions in the relevant x,Q2 domains. Finally, we briefly look at uncertainties related to the fit procedure, stressing their importance and using sW, sH and extractions of aS(MZ2) as examples. As a by-product of this last point we present a slightly updated set of parton distributions, MRST2002

Fracture Toughness of Composite and Unfilled Restorative Resins

Fracture toughness, critical strain energy release rate, and critical stress intensity factor were determined for experimental and commercial restorative resins. A composite resin had lower resistance to arack initiation than an unfilled acrylic resin. The data were consistent with surface failure observed in single-pass wear studies of these resins.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66920/2/10.1177_00220345770560070801.pd

Determining the Gluon Distributions in the Proton and Photon from Two-Jet Production at HERA

Two-jet production from the direct photon contribution at HERA is a sensitive measure of the small-$x$ gluon in the proton. We propose measurements of ratios of the jet cross-sections which will clearly distinguish between gluons with or without singular behaviour at small $x$. Furthermore, we show that analogous ratio measurements for the resolved photon contribution provide a sensitive way of determining the gluon distribution in the photon.Comment: Rutherford Appleton Laboratory report RAL-93-071 7 pages 3 figs Fig2 and Fig3 included as psfile

Quark Mass Textures and sin 2 beta

Recent precise measurements of sin 2 beta from the B-factories (BABAR and BELLE) and a better known strange quark mass from lattice QCD make precision tests of predictive texture models possible. The models tested include those hierarchical N-zero textures classified by Ramond, Roberts and Ross, as well as any other hierarchical matrix Ansatz with non-zero 12 = 21 and vanishing 11 and 13 elements. We calculate the maximally allowed value for sin 2 beta in these models and show that all the aforementioned models with vanishing 11 and 13 elements are ruled out at the 3 sigma level. While at present sin 2 beta and |Vub/Vcb| are equally good for testing N-zero texture models, in the near future the former will surpass the latter in constraining power.Comment: 1+20 pages, 2 figures, JHEP3 clas

Natural language processing to extract symptoms of severe mental illness from clinical text: the Clinical Record Interactive Search Comprehensive Data Extraction (CRIS-CODE) project.

OBJECTIVES: We sought to use natural language processing to develop a suite of language models to capture key symptoms of severe mental illness (SMI) from clinical text, to facilitate the secondary use of mental healthcare data in research. DESIGN: Development and validation of information extraction applications for ascertaining symptoms of SMI in routine mental health records using the Clinical Record Interactive Search (CRIS) data resource; description of their distribution in a corpus of discharge summaries. SETTING: Electronic records from a large mental healthcare provider serving a geographic catchment of 1.2 million residents in four boroughs of south London, UK. PARTICIPANTS: The distribution of derived symptoms was described in 23 128 discharge summaries from 7962 patients who had received an SMI diagnosis, and 13 496 discharge summaries from 7575 patients who had received a non-SMI diagnosis. OUTCOME MEASURES: Fifty SMI symptoms were identified by a team of psychiatrists for extraction based on salience and linguistic consistency in records, broadly categorised under positive, negative, disorganisation, manic and catatonic subgroups. Text models for each symptom were generated using the TextHunter tool and the CRIS database. RESULTS: We extracted data for 46 symptoms with a median F1 score of 0.88. Four symptom models performed poorly and were excluded. From the corpus of discharge summaries, it was possible to extract symptomatology in 87% of patients with SMI and 60% of patients with non-SMI diagnosis. CONCLUSIONS: This work demonstrates the possibility of automatically extracting a broad range of SMI symptoms from English text discharge summaries for patients with an SMI diagnosis. Descriptive data also indicated that most symptoms cut across diagnoses, rather than being restricted to particular groups

Concerning the quark condensate

A continuum expression for the trace of the massive dressed-quark propagator is used to explicate a connection between the infrared limit of the QCD Dirac operator's spectrum and the quark condensate appearing in the operator product expansion, and the connection is verified via comparison with a lattice-QCD simulation. The pseudoscalar vacuum polarisation provides a good approximation to the condensate over a larger range of current-quark masses.Comment: 7 pages, LaTeX2e, revtex

Extracting antipsychotic polypharmacy data from electronic health records: developing and evaluating a novel process

Background Antipsychotic prescription information is commonly derived from structured fields in clinical health records. However, utilising diverse and comprehensive sources of information is especially important when investigating less frequent patterns of medication prescribing such as antipsychotic polypharmacy (APP). This study describes and evaluates a novel method of extracting APP data from both structured and free-text fields in electronic health records (EHRs), and its use for research purposes. Methods Using anonymised EHRs, we identified a cohort of patients with serious mental illness (SMI) who were treated in South London and Maudsley NHS Foundation Trust mental health care services between 1 January and 30 June 2012. Information about antipsychotic co-prescribing was extracted using a combination of natural language processing and a bespoke algorithm. The validity of the data derived through this process was assessed against a manually coded gold standard to establish precision and recall. Lastly, we estimated the prevalence and patterns of antipsychotic polypharmacy. Results Individual instances of antipsychotic prescribing were detected with high precision (0.94 to 0.97) and moderate recall (0.57-0.77). We detected baseline APP (two or more antipsychotics prescribed in any 6-week window) with 0.92 precision and 0.74 recall and long-term APP (antipsychotic co-prescribing for 6 months) with 0.94 precision and 0.60 recall. Of the 7,201 SMI patients receiving active care during the observation period, 338 (4.7 %; 95 % CI 4.2-5.2) were identified as receiving long-term APP. Two second generation antipsychotics (64.8 %); and first -second generation antipsychotics were most commonly co-prescribed (32.5 %). Conclusions These results suggest that this is a potentially practical tool for identifying polypharmacy from mental health EHRs on a large scale. Furthermore, extracted data can be used to allow researchers to characterize patterns of polypharmacy over time including different drug combinations, trends in polypharmacy prescribing, predictors of polypharmacy prescribing and the impact of polypharmacy on patient outcomes

Mass Dependent αS\alpha_S Evolution and the Light Gluino Existence

There is an intriguing discrepancy between \alpha_s(M_Z) values measured directly at the CERN $Z_0$-factory and low-energy (at few GeV) measurements transformed to $Q=M_{Z_0}$ by a massless QCD \alpha_s(Q) evolution relation. There exists an attempt to reconcile this discrepancy by introducing a light gluino \gl in the MSSM. We study in detail the influence of heavy thresholds on \alpha_s(Q) evolution. First, we consruct the "exact" explicit solution to the mass-dependent two-loop RG equation for the running \alpha_s(Q). This solution describes heavy thresholds smoothly. Second, we use this solution to recalculate anew \alpha_s(M_Z) values corresponding to "low-energy" input data. Our analysis demonstrates that using {\it mass-dependent RG procedure} generally produces corrections of two types: Asymptotic correction due to effective shift of threshold position; Local threshold correction only for the case when input experiment lies in the close vicinity of heavy particle threshold: $Q_{expt} \simeq M_h$. Both effects result in the effective shift of the \asmz values of the order of $10^{-3}$. However, the second one could be enhanced when the gluino mass is close to a heavy quark mass. For such a case the sum effect could be important for the discussion of the light gluino existence as it further changes the \gl mass.Comment: 13, Late